Abstract

A COMPARATIVE REVIEW ON IN- VITRO ANTI- INFLAMMATORY ACTIVITY OF TURMERIC, GINGER AND LEMON GRASS

B. Sandhya Rani*, P. Anji Babu, K. Pravallika, S. K. Afrin, B. Aswini, B. Vamsi Krishna

ABSTRACT

Chronic inflammation is a hidden culprit behind many major diseases, such as arthritis, metabolic disorders, brain-related conditions, and cancer Plants like ginger (Zingiber officinale), turmeric (Curcuma longa), and lemongrass (Cymbopogon citratus) have been widely studied for their powerful anti-inflammatory effects. These plants contain active substances like gingerols, shogaols, curcuminoids, beta-carotene, vitamin A, and turmerones. These chemicals help reduce inflammation by controlling cytokine production, blocking the NFκB pathway, and lowering oxidative stress. There is a lot of research supporting their use in treating inflammatory diseases, but their poor absorption into the body is a challenge. New methods like using nanotechnology and combining these plants with others have shown promise in boosting their effectiveness. This review looks at how these plants work, the evidence from studies, their use in real-life situations, and future research needs. Even though these plants show promise, more large-scale clinical studies and better ways to deliver them are needed to make them effective treatments in modern medicine.

Keywords: inflammation, ginger, turmeric, clinical studies, metabolic disorders.