Abstract

DRUG NANOCARRIERS: INNOVATIONS IN CONTROLLED AND SUSTAINED RELEASE SYSTEMS

Shaik Sameer Basha*

ABSTRACT

Drug nanocarriers have emerged as a transformative platform in modern pharmaceutical sciences, offering precise control over drug delivery, release kinetics, and therapeutic targeting. Traditional dosage forms often face limitations such as poor solubility, rapid clearance, off-target effects, and systemic toxicity. Nanocarrier systems—including liposomes, polymeric nanoparticles, dendrimers, micelles, and solid lipid nanoparticles—provide significant advantages by enhancing bioavailability, enabling sustained and controlled drug release, and improving site-specific delivery. Recent innovations in surface functionalization, stimuli-responsive carriers, and ligand-based targeting have further expanded their clinical potential across oncology, infectious diseases, neurological disorders, and chronic conditions. This review provides an overview of the latest developments in drug nanocarriers, focusing on their design strategies, applications, challenges, and future directions.

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