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Abstract

NANOTECHNOLOGY IN OCULAR DRUG DELIVERY: A REVIEW

B. Premkumar*, K. Samunesh, M. Pradeepkumar, K. Karthick, S. Mohamed Shehal, G. Saroj, M. D. Swetha, D. Keshika and P. R. Roshan Khumaar

ABSTRACT

Effective ocular drug delivery remains a formidable challenge due to the complex structure of the eye and multiple protective barriers that restrict drug permeation and reduce bioavailability. Traditional delivery systems such as eye drops suffer from rapid precorneal elimination and limited drug penetration. Nanotechnology offers promising solutions by enabling enhanced bioavailability, prolonged residence time, targeted delivery, and reduced dosing frequency. This review presents an overview of various nanocarriers—such as nanoparticles, liposomes, dendrimers, nanomicelles, solid lipid nanoparticles, and nanostructured lipid carriers—and discusses their potential in treating a wide range of ocular diseases.

Keywords: Ocular drug delivery, nanotechnology, dendrimers, nanomicelles, lilipd carriers.


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