Abstract

STUDY ON THE ANTIOXIDANTS EFFECTS OF GUDUCHI IN DIABETIC WITH NONALCOHOLIC FATTY LIVER DISEASE

*Dr. Suhail Jandial - MD Kayachikitsa, Dr. Kshama Gupta MD - Sharir Rachana

ABSTRACT

Guduchi (Tinospora cordifolia) exhibits antioxidant properties that may be beneficial in managing diabetes and non-alcoholic fatty liver disease (NAFLD). Studies suggest Guduchi can help regulate blood sugar levels, improve insulin sensitivity, and protect the liver from damage. It also possesses antioxidant and anti-inflammatory properties, which are relevant to both conditions.Antioxidant Effects and Diabetes Guduchi contains various compounds with antioxidant activity, such as alkaloids, diterpenoid lactones, and phenolics. These compounds can help scavenge free radicals, reducingoxidative stress, a key factor in the development and progression of diabetes. Research indicates Guduchi can lower blood glucose levels, improve insulin sensitivity, and enhance glucose utilization in diabetic animal models. Studies have shown that Guduchi can normalize antioxidant enzyme levels (like SOD and CAT) that are altered in diabetes.Antioxidant Effects and NAFLD NAFLD is characterized by oxidative stress and inflammation in the liver. Guduchi's antioxidant and anti-inflammatory properties may help mitigate these effects in NAFLD. By reducing oxidative stress, Guduchi could potentially protect liver cells from damage and improve liver function.Overall Benefits: Guduchi has been traditionally used to support liver health, manage diabetes, and improve overall well-being.   Its antioxidant, anti-inflammatory, and antidiabetic properties make it a promising candidate for managing both diabetes and NAFLD. Further research is needed to fully understand the mechanisms and clinical efficacy of Guduchi in these conditions.

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