Abstract

A LITERATURE REVIEW ON ANTICONVULSANT DRUGS

*Karan Adak, Sneha Gurule, Ajay Maske, Sumit Thorat, Nilesh Jadhav

ABSTRACT

Epilepsy is a chronic neurological disorder characterized by recurrent, unprovoked seizures resulting from abnormal electrical activity in the brain. It affects millions globally and can significantly impact quality of life. Management of epilepsy primarily involves the use of anticonvulsant drugs (AEDs), which aim to control or reduce the frequency of seizures. These medications work by modulating neuronal excitability through various mechanisms, including enhancing inhibitory neurotransmission and inhibiting excitatory pathways. Common AEDs include phenytoin, carbamazepine, valproate, and newer agents like lamotrigine and levetiracetam. While AEDs are effective for many patients, treatment can be complex due to variability in drug response, side effects, and potential interactions. Recent advancements focus on personalized treatment approaches, improved drug formulations, and understanding the genetic underpinnings of epilepsy and drug response. Despite progress, achieving optimal seizure control and minimizing side effects remain significant challenges in epilepsy management.

Keywords: .