Abstract

BRIDGING GENOMICS AND TRADITION: AN INTEGRATIVE PERSPECTIVE ON PRECISION MEDICINE, EPIGENETICS, AND AYURVEDIC PRINCIPLES IN DIABETES MANAGEMENT

Dr. Shizra Shaikh* and Dr. Advait Menon

ABSTRACT

Diabetes mellitus, particularly type 2 diabetes mellitus (T2DM), poses a global health burden with complex genetic, environmental, and lifestyle determinants. As precision medicine and epigenetic research offer new paradigms for personalized healthcare, there is an emerging interest in integrating these biomedical frameworks with traditional systems of medicine. Ayurveda, India's ancient holistic health science, emphasizes individualized diagnosis and care based on constitutional types (Prakriti) and dosha imbalances. This paper investigates the conceptual and functional intersections between precision medicine, epigenetics, and Ayurveda in the context of diabetes. By exploring shared principles of individual variation, personalized intervention, and lifestyle modulation, we highlight the potential of a unified, integrativeapproach to managing diabetes. The convergence of 'omics' data with Ayurvedic phenotyping may pave the way for novel therapeutic and preventive strategies rooted in both ancient wisdom and modern biology.

Keywords: Precision medicine, gene expression, epigenetics, Prameha.