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Abstract

BIOTRANSFORMATION OF COUMARINS BY SACCHAROMYCES CEREVISIAE

Edijane Matos Sales, Tânia Fraga Barros and Eudes Da Silva Velozo*

ABSTRACT

This work describes the coumarins reduction (xanthotoxin and braylin) mediated by Saccharomyces cerevisiae strains in biphasic systems. The biotransformation of these compounds was regioselective and it allowed the formation of 5,6-dihydro-9-methoxy-7H-furo[3,2-g][1] benzopyran-7-one and 3',4'-dihydrobraylin.

Keywords: Biotransformation, biorreduction, braylin, regioselectivity, Saccharomyces cerevisiae, xanthotoxin.


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