Abstract

“UNLOCKING THE HEALING POTENTIAL OF PIPPALI (PIPER LONGUM LINN.)”: A REVIEW

Ketkee D. Nirmal*, Abhay Vyas and Kalyanee D. Nirmal

ABSTRACT

Piper longum Linn., commonly known as Pippali or long pepper, holds a significant place in Ayurvedic medicine as a potent carminative, rejuvenative, and respiratory tonic. Widely cited across classical texts and included in over 300 traditional formulations, Pippali has also served as a culinary spice with therapeutic value. Within the Ayurvedic framework, it is considered a pungent and heating herb, primarily used to balance Vata and Kapha doshas and to stimulate Agni (digestive fire). It is especially revered for its role in managing respiratory and digestive disorders and enhancing the bioavailability of other medicinal substances. However, classical sources like the Charaka Samhita caution against its prolonged use, noting its potential to aggravate doshas under certain conditions. Contemporary pharmacological studies have validated many of its traditional uses, identifying bioactive compounds such as Piperine, which exhibit anti-inflammatory, antioxidant, antimicrobial, hepatoprotective, and immunomodulatory properties. This article presents a comprehensive review of Pippali’s role in Ayurvedic medicine, its phytochemistry, and its relevance in modern therapeutic practices, bridging ancient wisdom with scientific insight.

Keywords: Pippali, Piper longum Linn, COVID-19.