Abstract

AN OVERVIEW OF GUILLAIN-BARRE SYNDROME

Dr. B. Senthilnathan, A.R. Sridevi*, Swetha Sugunan Pallithara, Jawaharsamuvel R., Karthikeyan G.

ABSTRACT

Guillain Barre Syndrome (GBS), an inflammatory disease of the central nervous system, is the most common cause of abrupt flaccid paralysis. The pathogens most frequently linked to GBS in case-control studies are Mycoplasma pneumoniae, Epstein-Barr virus, cytomegalovirus, Campylobacter jejuni, and hepatitis E virus. GBS is more common in elderly adults, and men are more likely to cause it than women. Most people recover from their symptoms without experiencing severe, long-term neurological effects, and they usually last a few weeks. It may affect speaking and swallowing ability, cause weakness or tingling sensations, or paralyze the limbs, legs, or face muscles. The possible treatment options for GBS are determined by the severity of the condition. For minor cases, there is currently no recommended course of treatment. For more severe instances, intravenous immunoglobulin and plasma exchange are the two possible therapeutic choices.

Keywords: Guillain Barre Syndrome, Campylobacter jejuni, hepatitis E virus, plasma exchange, intravenous immunoglobulin, Mycoplasma pneumonia.