Abstract

FORMULATION AND INVITRO EVALUATION OF TECOMA STANS FLOWER EXTRACTS TOPICAL OINTMENT FOR WOUND HEALING

Prathyusha Vuddanda1*, Sowmya Gayathri M., Anil Kumar S., Yashika S., Asma S. K. and Sai Kiran N.

ABSTRACT

Wound healing is a complex and dynamic biological process encompassing four overlapping phases: hemostasis, inflammation, proliferation, and remodeling. These stages work in concert to restore tissue integrity following injury. Conventional synthetic wound care agents, while effective, often present limitations such as high costs, potential allergic responses, and delayed healing outcomes. Consequently, there is a growing interest in natural and herbal alternatives that offer safer and more accessible options. Tecoma stans, commonly known as Yellow Bells or Trumpet Bush, is a traditionally used medicinal plant recognized for its antimicrobial, anti-inflammatory, and wound healing properties. This study focuses on the formulation and evaluation of a topical ointment incorporating flowerextracts of Tecoma stans to enhance wound management. The ointment was prepared using the fusion method with appropriate excipients and evaluated for key physicochemical parameters, including pH, viscosity, spreadability, texture, homogeneity, and stability. Further analyses, including antimicrobial and antioxidant activity assays, FTIR spectroscopy, and phytochemical screening, confirmed the presence of bioactive constituents such as flavonoids, alkaloids, saponins, and terpenoids compounds known to facilitate wound healing through various mechanisms. Literature evidence supports the extract’s efficacy in reducing inflammation, promoting wound contraction, and enhancing tissue regeneration. The findings of this study substantiate traditional claims and underscore the potential of Tecoma stans in developing an affordable, natural, and effective alternative to conventional synthetic wound healing agents. In conclusion, the formulated herbal ointment represents a promising candidate for integration into modern phyto pharmaceutical approaches to wound care.

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