Abstract

PRELIMINARY PHARMACOGNOSTICAL AND PHYTOCHEMICAL ANALYSIS OF ALSTONIA SCHOLARIS (DEVIL’S TREE)

Indrakesh Prajapati*, Jitendra Jena, Abhishek Yadav, Abdul Wadood Ansari and Km. Shveta Yadav

ABSTRACT

Alstonia scholaris, also known as the Devil’s Tree, has gained recognition for its significant role in traditional medicine. This medicinal plant from the Apocynaceae family has been widely used in Ayurveda, Unani, and other healing systems to manage ailments such as fever, malaria, dysentery, and skin conditions. Various parts of the plant, including its bark, leaves, and latex, are known for their therapeutic effects. The plant’s latex is applied to ulcers, sores, and tumors, while its bark is valued for its astringent, antipyretic, and cardiotonic properties. Phytochemical studies have revealed that A. scholaris contains a range of bioactive compounds such as alkaloids, flavonoids, tannins, glycosides, and steroids, which contribute to its diverse pharmacological activities. These include antimicrobial, antioxidant, antidiabetic, anticancer, and anti-inflammatory effects. Despite its medicinal potential, some plant components, especially its latex and certain alkaloids, are known to have toxic effects, underscoring the importance of proper preparation and controlled dosage. Further research is required to isolate its active constituents, understand their mechanisms, and conduct clinical trials to confirm its safety and effectiveness. This review provides an in-depth analysis of the traditional applications, phytochemistry, and therapeutic potential of Alstonia scholaris, while identifying key areas for future research and development.

Keywords: Alstonia scholaris, Devil’s Tree, Phytochemistry, Medicinal Plant, Traditional Medicine.