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Economic insect that are emerging as an ideal molecular Genetic resource for solving a broad range of biological problems. The silkworm, B. mori produces massive amount of silk proteins during the final stage of larval development. These proteins are stored in the middle silk gland and they are discharged through the anterior duct and spinneret, at the end of the fifth instar. Recently, silkworm is being used as bio factory for the production of useful protein using the silk gland, which has promoted the technological development in sericulture. With the above background silkworm can be classified as a value added biomaterial for medical application, application of silk protein fibroin and sericin as a biomaterial and other Seri-byproducts. Silk fibers have proven to be effective in many clinical applications. Silk fibroin based wound dressing that could accelerate healing and could be peeled off without damaging the newly formed skin. Subsequently the wound dressing was made with a mixture of both fibroin and sericin .The present paper overviews some important studies carried out on sericin and fibroin of silkworm, Bombyx mori Linn.

Keywords: Sericin, Fibroin, Bombyx mori.

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