Abstract

PHYTOCHEMICAL SCREENING OF SCOPARIA DULCIS LINN. SCROPHULARIACEAE AND IN SILICO BIOACTIVITY STUDY OF ISOLATED COMPOUNDS

Chandresh Maurya*, Dr. Jitendra Malik, Shivam Raikwar and Gyan Singh

ABSTRACT

The plant Scoparia dulcis Linn. belongs to the family Scrophulariaceae, Known as a sweet broom, Scoparia dulcis Linn. is a tropical American natural plant that is a member of the Scrophulariaceae family. Its anti-diabetic, antipyretic, antihypertensive, and diuretic properties were recognized by traditional healers, who have used it to create a number of promising traditional medications and formulations. By using preliminary phytochemical analysis, column chromatography to separate active chemicals, and spectrum analysis such as UV, IR, NMR, and MASS spectra to describe the isolated component, the current study's primary goal is to identify the phytoconstituents contained in the leaf extract. The plant has more phytochemicals, including carbohydrates, alkaloids, tannins, phenols, flavonoids, vitamin C, and amino acids, according to the early phytochemical analysis. According to the quantitative calculation, it contains a significant amount of flavonoids, phenols, and vitamins C. To separate the phytoconstituents, the ethanol extract was made and used in through chromatography. It was found that the percentage of acetone:ethanol (60:40) and (40:60) included a dull white crystalline substance. Spectral analyses were performed on this substance. The spectrum investigations suggest the existence of several functional groups from the elemental analysis. It is possible to identify the separated compound's chemical makeup based on the spectrum analyses. Future research might also focus on identifying novel chemicals and their potential medical uses.

Keywords: anti-diabetic, antipyretic, antihypertensive, traditional medications, phytoconstituents.