Abstract

PHYSICOCHEMICAL CHARACTERIZATION AND QUALITY EVALUATION OF FLEXI NECK SOFT GEL CAPSULES: A POLYHERBAL AYURVEDIC FORMULATION FOR CERVICAL AND JOINT SUPPORT

Anu Joy*, Reeshma C. R., Smitha Francis and Adithya Peethambara Panicker

ABSTRACT

Introduction: Ayurveda, an ancient holistic system of medicine, views cervical spondylosis as a vata dosha imbalance, requiring therapies that restore balance, improve circulation, and support joint health. Flexineck softgel capsules, developed by Sitaram Ayurveda, blend traditional Ayurvedic herbs with modern formulation techniques to provide effective relief from cervical spondylosis. Materials and Method: This study evaluates Flexineck’s organoleptic, physicochemical, phytochemical, microbial, and HMT safety parameters to ensure its efficacy, safety, and stability, highlighting the importance of scientifically validated Ayurvedic formulations. Result: Flexineck soft gel capsules exhibited acceptable organoleptic properties with a light green color, characteristic odor, and oily texture. Physicochemical analysis confirmed chemical stability with an RI of1.470, low acid (2.4) and peroxide (0.78) values, and a dissolution time of 10 minutes. Phytochemical screening revealed the presence of carbohydrates, sugars, glycosides, and steroids, while proteins, flavonoids, and terpenoids were absent. TLC profiling demonstrated multiple Rf values consistent with key raw materials. Microbial analysis confirmed the absence of pathogenic organisms, and heavy metals, pesticides, and aflatoxins were all below detectable limits, indicating the product's safety and purity. Overall, the results support the structural integrity, chemical stability, and safety of Flexineck soft gel capsules for consumption. Conclusion: Flexineck soft gel capsules exhibit strong quality, safety, and therapeutic potential, validated through comprehensive organoleptic, physicochemical, phytochemical, and safety analyses. These findings support its use as a stable, contaminant-free, and bioactive Ayurvedic formulation for managing cervical spondylosis and promoting joint health.

Keywords: Flexineck soft gel capsules, Cervical spondylosis, Joint pain, Heavy metal analysis, Aflatoxin.