Abstract

SEVERE ACUTE RESPIRATORY SYNDROME (SARS) – A REVIEW

Manu Priya, *Jasmine Dhiman, Sanjiv Duggal

ABSTRACT

Severe Acute Respiratory Syndrome (SARS), caused by the SARS coronavirus (SARS-Co V), emerged as a global health crisis in 2003, leading to over 8,000 reported cases and nearly 800 deaths worldwide. The virus, transmitted primarily through respiratory droplets, posed significant challenges to healthcare systems, triggering widespread public health measures. Despite the eventual containment of the outbreak, the emergence of SARS-CoV-2 in 2019 has highlighted the ongoing threat posed by coronaviruses. This article reviews the pathogenesis, transmission dynamics, and clinical management strategies employed during the SARS-Co V outbreak, emphasizing lessons learned that continue to inform the response to contemporary coronavirus-related diseases. Through a comprehensive examination of virology, epidemiology, and clinical treatment protocols, this paper highlights key factors contributing to the spread of SARS-CoV and its clinical manifestation as a rapidly progressing pneumonia. Particular attention is paid to the role of early diagnosis, quarantine measures, and antiviral treatments in mitigating disease spread and mortality. Additionally, the article explores advancements in diagnostic technologies and the development of vaccines in response to the 2003 SARS outbreak, laying a foundation for more effective control mechanisms in future corona viral pandemics. Finally, the paper discusses the continuing relevance of SARS-CoV research in the context of global health security, offering recommendations for improving preparedness in the face of potential new coronaviruses. The future aspects of severe acute respiratory syndrome (SARS) are focused on developing effective treatments, vaccines, and diagnostic tools. Researchers are working on creating robust coronavirus vaccines ad vectors platforms, as well as investigating the correlates of protection against SARS-Co V and other severe lower respiratory tract human coronavirus infections.

Keywords: SARS-Cov, pathogenesis, transmission, epidemiology, vaccine development.