Abstract

A REVIEW OF MICROCRYSTALLINE CELLULOSE: STRUCTURE, APPLICATIONS, AND LIMITATIONS

Awais Khan* and Aditi Patil

ABSTRACT

Microcrystalline cellulose usage in various fields, such as food, pharmaceutical, medical, cosmetic and polymer composites industries.[2] Microcrystalline cellulose has recently gained more interest owing to its renewability, non-toxicity, economic value, biodegradability, high mechanical properties, high surface area and biocompatibility.[1,2] Microcrystalline cellulose functions as a binder, disintegrant, texturizer, and stabilizer. Additionally, it also addresses current limitations in microcrystalline cellulose use, such as moisture sensitivity and compatibility with certain polymeric matrices.[2] Microcrystalline cellulose is one of the most important tablet excipients to its outstanding dry binding properties, enabling the manufacture of tablets by direct compression.[3] Microcrystalline cellulose based active films offer an innovative approach to extendingthe shelf life of food products by delivering antimicrobial protection and inhibiting lipid oxidation.[4] This review explores the structure microcrystalline cellulose, its diverse applications, and the associated limitations that may impact its utility.

Keywords: Microcrystalline Cellulose (MCC), Structure, Pharmaceutical Excipient, Limitations, Food Additives.