Abstract

A REVIEW OF NANOGELS AS MODERN HERBAL DRUG DELIVERY THERAPY

Bhavana Singh* and Maneesh Kumar Singh

ABSTRACT

Nanogels have developed into a versatile hydrophilic platform for encasing guest molecules with a broad range of possible applications due to their capacity to respond to external stimuli. These soft materials can be employed for both therapy and disease imaging because of their crosslinked networks, which can contain biomacromolecules, inorganic nanoparticles, and small molecular medicines. By selecting the appropriate constituent polymer and crosslinker components to regulate their stimuli-responsive behavior and generate the desired response at the site of action, nanogels can actively participate in the intended function of the carrier system rather than acting as passive carriers of their cargo. A hydrogel nanoparticlehaving a network of cross-linked hydrophilic polymers is referred to as "nanogel." Cross-linked polymers are used to create nanogels, which are nanoparticles thatswell in the right solvent. Because of their tiny size, nanogels exhibit superior penetrationcharacteristics and a strong drug loading capacity. Numerous routes, including oral, nasal,parenteral, pulmonary, intraocular, etc., can be used to administer them. Because of itscomfort and stability, nanogel is preferred for herbal remedies. Because of their high drugencapsulation capacity, uniformity, low toxicity, and increased stability, nanoges are apromising and innovative approach to herbal medications that may also be referred to asfuture generation drug delivery systems.

Keywords: Herbal medicine, Nanogel.