Abstract

GENOTOXICITY STUDY OF LAMBDACYHALOTHRIN IN WISTAR ALBINO RATS

Bhoopendra Kumar* and Nitesh Kumar

ABSTRACT

Genotoxicity study of lambda-cyhalothrin was conducted in wistar albino rats. The micronucleus and chromosomal aberration test were conducted @ dose level of 20 mg/kg b.wt. Whereas for bacterial reverse mutation test (Ames test) four dose levels 5, 100, 1000 and 5000 μg/plate were selected. The Salmonella typhimurium TA98, TA100, TA1535, TA97a and E. coli WP2 (uvra) bacterial strains respectively were used. The result indicated that lambda-cyhalothrin significant (p

Keywords: lambda-cyhalothrin, micronucleus, chromosomal aberration, bacterial reverse mutation.