Abstract

UV-SPECTROPHOTOMETRIC DETERMINATION OF GLYCYRRHETINIC ACID IN TAVERNIERA CUNEIFOLIA AND ABRUS PRECATORIUS

Mamta B. Shah*, Parth V. Patel, Keval D. Prajapati, Jayesh K. Sindhal, Devang N. Soni and Krish B. Patel

ABSTRACT

The present research investigates a cost-effective method for the estimation of glycyrrhetinic acid in chloroform extracts of Taverniera cuneifolia and Abrus precatorius using UV-spectrometry. These plants present viable alternatives to Glycyrrhiza glabra, which is the conventional source of glycyrrhetinic acid. Traditionally, the quantification of glycyrrhetinic acid is done using high-performance liquid chromatography (HPLC) and high-performance thin-layer chromatography (HPTLC), both of which are known for their accuracy but are also associated with high operational costs. This study demonstrates that UV-spectrometry is not only a simpler and more affordable technique but also produces results closely aligning with those obtained from HPLC and HPTLC. The findings highlight the reliability and practicality of UV-spectrometry as an accessible alternative for glycyrrhetinic acid analysis. By establishing its cost-effectiveness and precision, this study underscores the potential of UV-spectrometry to facilitate widespread application in the analysis of glycyrrhetinic acid from alternative plant sources.

Keywords: Abrus precatorius, glycyrrhetinic acid, Taverniera cuneifolia, UV-spectrometry.