Abstract

RP HPLC DISSOLUTION METHOD FOR ESTIMATION OF FLURALANER IN CHEWABLE TABLES FOR DOGS

*Bhavesh Patel, Viral Shah, Prakash Katariya, Niraj Kansara, Surendra Singh Saurabh, Nishit Rana, Prachi Patel, Vraj Patel, Gautam Pancholi, Pushkar Patel, Ishu Rathwa, Naimisha Patel, Bhargav Lakod, Megha Shah and Ankit Bhatt

ABSTRACT

Dissolution testing is an essential part of the pharmaceutical quality assurance process, measuring the rate and extent to which the active pharmaceutical ingredient (API) is released from its dosage form in vitro. It is a key determinant of drug bioavailability and, by extension, therapeutic efficacy. With its pivotal role in drug development, dissolution testing requires precise development and validation of methods to ensure consistency, reliability, and compliance with regulatory standards. This review explores the dissolution method of Fluralaner chewable tablets, including the selection of dissolution medium, apparatus choice, and design parameters that influence dissolution outcomes. Additionally, the review addresses HPLC analytical method for Fluralaner Chewable Tablets.

Keywords: Fluralaner, HPLC, Dissolution and active pharmaceutical ingredient.