Abstract

ANTIDIABETIC ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF CASSIA ANGUSTIFOLIA BY USING LEAF EXTRACT

K. Srikanth Reddy*, Dr. P. Vasanth Kumar, V. Anil Kumar, R. Chaithanya, K. Kalpana, M. Chaithanya, S. Lakshmi, K. B. Archana and G. Hemalatha

ABSTRACT

Type 2 Diabetes Mellitus(T2DM) is very common metabolic disorder affecting people of all age groups. The change in life style and environmental factors are the considerable factors which are involved in the development of disorders. The different parts of medicinal plants vary in their composition of bioactive compounds. There are reports on antidiabetic activity of Cassia angustifolia flowers and leaves. This study aims to explore the antidiabetic efficiency of flowers and leaves and to identify the different composition of phycompounds present in flowers and leaves parts were identified using microscope uv spectroscopy phytochemical analysis showed the presence of various flavonoids, tannins, alkaloids, phenols and steroids compounds specific to leaves and flowers parts Cassia angustifolia Vahl. (Senna) is a medicinal plant containing anthraquinone compounds such as sennoside. Senna is primarily valued for its laxative properties. In Persian medicine, this plant has been also used to treat various disorders such as diabetes and skin hyperpigmentation. Previous studies have shown that different species of senna, such as C. articulata, C. alata, C. Siamea, C. Surattensis inhibit alpha-amylase and α-glucosidase enzymes. To the best of our knowledge, no previous evidence is available on tyrosinase and α-glucosidase inhibitory effects of the extract and different fractions of C. Angustifolia leaves.

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