Abstract

EXPLORING HERBAL THERAPEUTICS FOR POST-VIRAL FATIGUE SYNDROME: AN EVIDENCE-BASED REVIEW

Virendra R. Pardeshi*, Nilesh P. Patil and Ravindra R. Patil

ABSTRACT

After a viral infection, immunological failure, chronic inflammation, and ongoing exhaustion are the hallmarks of post-viral fatigue syndrome (PVFS), a complicated condition. Because traditional medication often fails to adequately address the complicated nature of PVFS, interest in herbal medicines as additional therapies has increased. Eight well-studied herbal medications with immunomodulatory, anti-inflammatory, adaptogenic, and antioxidant properties may be useful in the treatment of PVFS, per this study. The adaptogenic qualities of Withania somnifera, commonly referred to as ashwagandha, are well known for their ability to alleviate stress-induced exhaustion and increase resilience. Often referred to as ginseng, Panax ginseng improves energy metabolism and suppresses the immune system to promote recovery. The benefits of rhodiola rosea include a reduction in the symptoms of weariness and an improvement. For respiratory recuperation, liquorice (Glycyrrhiza glabra) is a great aid due to its potent antiviral and anti-inflammatory qualities. Through the regulation of pro- and anti-inflammatory cytokines, guduchi (Tinospora cordifolia) maintains immunological homeostasis. Because of its strong anti-inflammatory and antioxidant qualities, holy basil (Ocimum sanctum) helps to lessen oxidative stress and fatigue. Curcumin, the main component of turmeric (Curcuma longa), combats systemic inflammation and oxidative damage to aid in healing. The numerous bioactive compounds in moringa (Moringa oleifera) that support immunological and tissue healing include vitamins and antioxidants. The review focuses on the pharmacological properties of various herbal medicines and how they may be used in combination to treat the root causes of PVFS. By integrating pharmaceutical treatments into therapeutic procedures, dependence on conventional treatments may be reduced, thereby offering a successful, thorough, and safe approach to rehabilitation.

Keywords: Post-viral fatigue syndrome (PVFS), oxidative stress, herbal remedies, viral infections, chronic inflammation and therapeutic approaches.