Abstract

IDENTIFICATION OF BIOACTIVE COMPOUNDS FROM MARINE SPONGE – SPONGIA TOSTABY GC –MS ANALYSIS

Archana.R, Kanchana.G*, Rubalakshmi.G

ABSTRACT

The Ocean is the mother of life and it is believed that the most primitive forms of life originated from this “primordial soup”. The marine environment is a rich source of bioactive compounds. This study was carried out to analyse the active constitutents from Marine Sponge using Gas Chromatography - Mass spectrometry. The chemical composition of the methanolic extract of Spongia Tosta was investigated using Perkin Elmer gas chromatography mass spectrometry. Mass spectra of the compound found in the extract were matched with the National Institute of Standard and Technology (NIST) library. This analysis revealed that Spongia Tosta contains ten bioactive compounds which included 1-Iodo, 2-methylnonane, n-Hexadecanoic acid, 4 -Dodecanol, 9 - Oxabicyclo [ 6.1.0 ] nonane, 3- Hexanol, 2, 2-dimethyl, 1, 4 -Hexadiene, 3, 3, 5 - trimethyl, Oleic acid, Octanal, 7-methoxy-3,7-dimethyl, Spiro [androst-5-ene-17, 1’-Cyclobutan]-2’-one,3-hydroxy [3a’,17a’],and Diazoprogesterone. Hence the present study reveals that a Marine Sponge - Spongia Tosta can serve as a potential source for current biomedical and pharmaceutical importance.

Keywords: Marine Sponge - Spongia Tosta, Bioactive Compounds, Gas Chromatography and Mass Spectrum