Abstract

SYSTEMIC REVIEW ON EFFECT OF HERBAL DRUGS ON TUBERCULOSIS (TB)

Mayur R. Chavan, Kunal D. Girase, Goraksha S. Chavhan*, Ravindra R. Patil and Manish B. Kokani

ABSTRACT

Tuberculosis (TB) remains a pervasive global health concern, affecting millions of people worldwide, particularly in daeveloping countries. Despite significant advancements in conventional treatments, real-world outcomes often fall short of expectations due to patient variability, coexisting conditions, and incomplete treatment adherence. In pursuit of innovative solutions, this review delves into the potential of natural remedies, encompassing Indian licorice, turmeric, ashwagandha, and other traditional plant-based therapies, in combating TB. These plants have been found to exhibit a plethora of anti-tuberculosis properties, including immunity enhancement, anti-inflammatory, antibacterial, and immunomodulatory effects. The bioactive compounds present in these plants, such as glycyrrhizin, curcumin, and withanolides, have demonstrated significant therapeuticpotential against Mycobacterium tuberculosis. This review aims to provide a comprehensive overview of the current state of knowledge regarding the anti-tuberculosis properties of traditional plant-based therapies, highlighting their potential as adjunctive treatments or alternatives to conventional therapies. Furthermore, this review underscores the need for rigorous scientific investigation and clinical validation to fully harness the therapeutic potential of these natural remedies, ultimately contributing to the development of more effective strategies for combating TB globally.

Keywords: Tuberculosis (TB), Traditional medicine, Immunomodulatory, Antibacterial, Anti-inflammatory.