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FORMULATION AND EVALUATION OF PRULIFLOXACIN SUSTAINED RELEASED TABLETS
Shaik Yasmin, CH. Saibabu, K. Thejomoorthy*
ABSTRACT From the formulations prepared by direct compression method by using microcrystalline cellulose, xanthan gum, HPMCK15M, carbopol, lactose, magnesium stearate and talc. The tablets prepared were found to be within the official limits with respect to weight variation, thickness, hardness, friability, disintegration and dissolution. The stability study was performed for F5 formulation as per ICH guidelines. Stability study was carried out for 3 months at 40°C/75%RH. The tablets were tested for release and results were found within the limits. Among the all formulations the release profile of formulation F5 was found to be similar to the marketed product release profile. Keywords: The stability study was performed for F5 formulation as per ICH guidelines. [Download Article] [Download Certifiate] |
