Abstract

MEDICINAL PLANTS HAVING ANTI-ULCER ACTIVITY

Anurag*, Anmol, Mukesh Sharma, Manish Kumar and Dr. Aasha Gandhi

ABSTRACT

Ulcers are an open sore of the skin or mucus membrane characterized by sloughing of inflamed dead tissue.[1] Ulcers are lesions on the surface of the skin or a mucous membrane characterized by a superficial loss of tissue. Ulcers are most common on the skin of the lower extremities and in the gastrointestinal tract, although they may be encountered at almost any site. There are many types of ulcers such as mouth ulcer, oesophagus ulcer, peptic ulcer, and genital ulcer. Of this peptic ulcer is seen among many people. The peptic ulcers are erosion of lining of stomach or the duodenum.[2] The two most common types of peptic ulcer are called ―gastric ulcer‖ and ―duodenal ulcer.‖ The name refers to the site of ulceration. A person may haveboth gastric and duodenal ulcers at the same time. Gastric ulcers are located in the stomach, characterized by pain; ulcers are common in older age group. Eating may increase pain rather than relieve pain. Other symptoms may include nausea, vomiting, and weight loss. Although patients with gastric ulcers have normal or diminished acid production, yet ulcers may occur even in complete absence of acid.[3] Duodenal ulcers are found at the beginning of small intestine and are characterized by severe pain with burning sensation in upper abdomen that awakens patients from sleep. Generally, pain occurs when the stomach is empty and relieves after eating. A duodenal ulcer is more common in younger individuals and predominantly affects males. In the duodenum, ulcers may appear on both the anterior and posterior walls.[4] In some cases, peptic ulcer can be life threatening with symptoms like bloody stool, severe abdominal pain, and cramps along with vomiting blood.[5]

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