Abstract

REVIEW ARTICLE NANOFIBER: CURRENT NOVEL DRUG DELIVERY SYSTEM

Pranali P. Lade*, Sejal S. Kamble, Asmit N. Kamble and Mayuri B. Jadhav

ABSTRACT

Nanofibers are fibers with diameters in the nanometer range (typically, between 1nm and 1μm). Nanofibers can be generated from different polymers and hence have different physical properties and application potentials. Nanofibers possess extremely high specific surface area and surface area-to-volume ratio. They are capable of forming networks of highly porous mesh with remarkable interconnectivity between their pores, making them an attractive choice for a host of advanced applications The formulation was subjected to its characterization as UV, FT-IR, particle size, zeta potential, SEM, XRD and % drug release of formulation. From, the above study its revealed that electrospinning folic acid, polyvinylpyrrolidone, and extract-loaded nanofiber enhanced anticancer activity by increasing pharmacokinetic properties due to its low particle size.

Keywords: Nanofibers; polymers; electrospinning.