Abstract

PHYTOCHEMICAL ANALYSIS OF ANDROGRAPHIS PANICULATA (KALMEGH) AND STUDY OF ITS ANTIBACTERIAL ACTIVITY IN-VITRO

Saikat Manna, Arpan Maity, Anirban Dutta and Somnath De*

ABSTRACT

An essential herb for the tribal people that hasn't been discovered as vividly as it is today is Andrographis paniculata. There has been no research on phytochemical screening, with the exception of a few fragmentary findings. Furthermore, current antibacterial activity has not been conducted with this consideration in mind. Recently, acetone, ethanol, and aqueous solvent extracts were used for phytochemical screening and antibacterial efficacy against four bacteria (S. typhi, P. aeruginosa, K. pneumoniae, and B. subtilis). Flavonoids as a phytochemical marker were shown to produce the best results, with ethanol extract for P. aeruginosa and acetone extract for B. subtilis demonstrating superior outcomes compared to extract in aqueous solution.

Keywords: Andrographis paniculata, Phytochemical analysis, Anti- bacterial effect, Zone of inhibition, Agar-well-diffusion.