Abstract

LIPOSOME-BASED NANOPARTICLE SYSTEMS: A COMPREHENSIVE REVIEW OF LIPOIDAL DRUG DELIVERY INNOVATIONS

Avani Farasrami*

ABSTRACT

Liposome-based nanoparticles have become a cornerstone in modern drug delivery, offering significant advantages in the encapsulation and targeted delivery of therapeutic agents. These spherical vesicles, composed of lipid bilayers, enhance the bioavailability and reduce the toxicity of drugs, particularly in the treatment of cancer and infectious diseases. This review provides a comprehensive overview of the design, formulation, and clinical applications of liposome-based nanoparticle systems. It discusses the advantages of these systems, the challenges in their development, and recent innovations such as stealth liposomes, stimuli-responsive liposomes, and hybrid liposomes. Furthermore, the review highlights the potential of these nanoparticles in overcoming the limitations of traditional drug delivery methods, particularly in oncology.

Keywords: Liposome-Based Nanoparticles, Drug Delivery Systems, Cancer Therapy, Stealth Liposomes, Stimuli-Responsive Liposomes, Hybrid Liposomes, Nanotechnology.