Abstract

FORMULATION AND EVALUATION OF ALOEVERA GEL

N. Indu Hasini, P. Indhu, R. Anuhya, S. Harika and Nagineni Sudarshan Rao*

ABSTRACT

The aimed of current research to formulate tooth gel utilizing leaf extract of Aloevera. In multiple clinical studies, Aloevera has used in dentistry for wound-healing effect, gingivitis, plaque control and curing oral mucosal lesions. Aloevera is natural, ancient ingredient. The formulated Aloevera tooth gel evaluated by physical examination: Co-lour-yellowish brown, Appearance-Homogeneous, smooth nature, Transparency-translucent and Relative density-10.5, No microbial growth in sample plate, pH-7.5, Viscosity-3100cp, Extrudability amount percent-91.33, Spreadability-6.5cm/sec and observed good stability. The antimicrobial evaluation against Staphylococcus aureus reveal that formulated aloe vera tooth gel exhibited notable activity with ZOI of 19.5 mm at MIC of 25μg/mL. The outcome from this research evidently signified that the natural plant Alo vera using to formulate tooth gel may be a new approach to formulate tooth gel economically and minimum side effect than synthetic formulation and good scope in future about dental research in natural remedies.

Keywords: Aloevera, leaves extract, tooth gel, anti-microbial, ZOI, comparative study, dental.