Abstract

ALLIUM SATIVUM L. IT'S THERAPEUTIC USES AND POTENTIAL USE AS AN ANTICANCER AGENT: A REVIEW

Madhav Kumar Mishra*, Abhishek Rajput, Madhulika Krishan Yadav, Shweta Sinha, Roushan Bhaskar and Prakash Pralhad Sarwade

ABSTRACT

There are a number of plants that belong to the genus Allium, including onions, garlic, leeks, chives, and shallots. This genus has a long history of recognising the potential health benefits of these plants, particularly in terms of preventing cancer and oxidative stress. Among them, onions and garlic have been the focus of the most research, which has led to the discovery of biological activity that suggests they have the potential to be effective anticancer medications and antioxidants. According to the findings of research, allium species include a large number of bioactive compounds. These chemicals have anti-oxidative properties and can target cancer cells in a variety of different ways. Organosulfur compounds (OSCs), allicin, flavonoids, and other compounds with comparable properties possess potent antioxidant and anticancer properties. These chemicals have the ability to trigger cell death, halt the cell cycle, and prevent the growth oftumours. The anti-inflammatory and antioxidant characteristics that they possess further strengthen the potential that they have as a treatment for cancer. Not just garlic and onions, but also other species of Allium have been revealed to have similar biological activity, according to research conducted on these plants. This indicates that there is a comprehensive range of natural products that have the potential to be utilised in the development of new cancer treatments. In the field of pharmaceutical research and dietary treatments, a deeper understanding of the numerous applications of allium plants can be of considerable help. This understanding can lead to the development of novel approaches to the treatment and prevention of cancer as well as oxidative stress.

Keywords: Allium sativum, Therapeutic uses, Anticancer agent.