Abstract

A REVIEW: SYNTHESIS OF CHALCONE BY DIFFERENT REACTIONS AND THEIR EFFICACIOUS BIOLOGICAL APPLICATION

P. V. Badadhe*, A. S. Shinde, C. D. Ingale and S. P. Kunde

ABSTRACT

Chalcone is a pioneer in the field of polyphenols, mostly composed of flavonoids, an aromatic ketone that is widely distributed in plants. It is at the centre of a large number of important chemicals with biological functions. The features of chalcone rings, such as their antibacterial, antioxidant, antiulcer, anthelmintic, antiviral, anticancer, insecticidal, and antiprotozoal effects, are attributed to their α, β-unsaturated carbonyl system. Chalcones can be produced using a variety of methods, including the Schiff base reaction, Suzuki coupling, Heck's reaction, and Claisen-Schmidt condensation. In a nutshell, this thorough analysis aims to highlight the synthesis process of chalcones while delving into their diverse biological roles.

Keywords: Chalcone, Synthesis, Reactions, Condensation, Biological applications.