Abstract

REVIEW ON: DETECTION OF CARCINNOGENIC NITROSAMINE IN WATER USING GC/MS AND HPLC WITH TLPE

Apurva Gobare*, Dr. Suhshma Vaishanav, Dr. Pravin Wakte and Sachin Bhusari

ABSTRACT

Nitrosamines (NAs) are extremely powerful cancer-causing substances that have been found in different types of food and samples from the environment. This study introduces a direct gas chromatography/mass spectrometry (GC/MS) technique for detecting NAs in drinking water and swimming pools. The suggested technology utilizes tandem liquid-phase extraction (TLPE) in conjunction with high-performance liquid chromatography (HPLC) to effectively distinguish and identify fourteen N-nitrosamine species. The study showcases the effectiveness of this method in several food-simulating liquids, such as water, 3% acetic acid, 10% ethanol, and 50% ethanol. The new method offers a dependable and responsive approach for monitoring NAs, thereby aiding in the comprehension and reduction of these cancer-causing pollutants in both drinking water and recreational water settings.

Keywords: Nitrosamines (NAs), Carcinogens, Detection, Gas chromatography/mass spectrometry (GC/MS), Tandem liquid-phase extraction (TLPE), High-performance liquid chromatography (HPLC), N-nitrosamine species.