Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS MARCH ISSUE PUBLISHED
  • MARCH 2020 Issue has been successfully launched on 1 March 2020.

Abstract

DIABETIC NEPHROPATHY: A REVIEW OF CURRENT AND FUTURE PROSPECTIVE

Atul Arya*, Surbhi Rana, Dr. Randhir Singh, Dr. Lakhwinder Singh

ABSTRACT

Diabetic nephropathy is the single most common cause of end-stage renal disease in the world characterised by albuminuria, elevated blood pressure, and a persistent loss of renal function and is associated with greatly increased morbidity and mortality. Adequate control of blood pressure is of paramount importance in delaying the progression of renal disease in diabetic patients. Drugs acting on renin angiotensin aldosterone axis are of proven value in diabetic nephropathy. Particularly angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) have benefits beyond blood pressure control. The disease can be detected by raised urinary albumin excretion microalbuminuria. This allows time for the intensive treatment of glycaemic control, blood pressure and other cardiovascular risk factors, such as lipids, to reduce the morbidity and mortailty. Blockade of the renin-angiotensin-aldosterone system (RAAS) prevents the development and progression of diabetic nephropathy. For patients with high risk of progressive kidney disease potential benefits of dual RAAS blockade on an individual basis will be beneficial. If therapeutic goals are not achieved with an angiotensin converting enzyme inhibitor or angiotensin receptor blockers, then the addition of a nondihydropyridine CCB should be considered. The ever-increasing incidence of diabetic nephropathy has major implications for both patient welfare and health care resources at a time when renal services are already struggling to cope with current demands. However, numerous treatment strategies have been identified that delay the progression of renal disease in diabetes, which is also associated with improved patient Survival.

Keywords: Diabetic nephropathy, Renin angiotensin aldosterone system, Angiotensin


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More