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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2020
Citation	6651	4087
h-index	26	21
i10-index	174	83

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2025 Issue has been successfully launched on 1 NOVEMBER 2025.

Abstract

AN ANALYTICAL METHOD FOR THE ESTIMATION OF THIOCOLCHICOSIDE AND ACECLOFENAC IN PHARMACEUTICAL DOSAGE FORMS

Pradeep Kumar*

ABSTRACT

A new RP- HPLC method was developed and validated for the estimation of aceclofenac and thiocolchicoside in their tablet dosage form. The chromatographic separation was carried out by using Agilent Zorbax column (150 × 4.6mm, 5μm). The mobile phase containing the combination of methanol & 0.1% ortho phosphoric acid in the 75: 25 (v/v) ratios. In this method the ow rate used is 1 min/ml for the separation at the detection wavelength of 275 nm. The proposed method was validated according to the ICH guidelines. The method was linear (R2 >0.99), precise (RSD < 2.0%), accurate, simple, sensitive and robust. This method can be successfully used for the routinepharmaceutical analysis.

Keywords: Thiocolchicoside; Aceclofenac; RP- HPLC; Method development; Validation.

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