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Abstract

PHYTOCHEMICAL CONSTITUENTS AND BIOACTIVITY OF DIFFERENT PLANTS FROM GULMI DISTRICT OF NEPAL

Bimala Subba* and Rishi Ram Paudel

ABSTRACT

Phytochemical and biological screenings of some medicinal plants like Schima wallichii, Psidium guajava, Bauhinia variegata, Rubia cordifolia and Artocarpus lakoocha of Gulmi district were performed. Potent pharmacological activities were revealed by bark of S. wallichii and leaves of P. guajava. Methanol extracts of bark of S. wallichii and leaves of P. guajava exhibited high toxicity against brine shrimp nauplii at LC50 (μg/ml) values of 31.612 and 25.174 respectively. Similarly, leaves of P. guajava (94.391 mM Fe+2/liter) and bark of S. wallichii (73.669 mM Fe+2/liter) were found to have strong antioxidant power. In addition, S. wallichii leaves, P. guajava and B. variegate
exhibited high antibacterial activities against Staphylococcus aureus and Escherichia coli.

Keywords: Methanol extracts, phytochemical screening, biological activities, S. wallichii, P. guajava.


[Full Text Article]

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