Abstract

A REVIEW ON NANOGELS AND THEIR APPLICATIONS ON DERMAL THERAPY

Pranav Malagar*, Nitan Bharti Gupta, Hardeepkaur, Pooja Sharma and Manjit Kaur

ABSTRACT

A nanogel is a cross-linked nano-sized, a realistic network of hydrophilic polymers with an capacity to swell by holding large amount of water while preserving the structure due to chemical or physical cross-linking of single polymer chains. Nanogels can be prepared of artificial and/or natural polymers resulting in a cationic, anionic, or neutral system liable on the bound groups’ charges. Currently, these materials are receiving incredible attention in research due to their properties. They are widely investigated as carriers in the biomedical field. At present, there is an expansion of research into dermatologic treatment due to a serious need for new treatment options to treat skin diseases. The skin itself provides a natural hurdle against
particle penetration for topical delivery. However, it also offers a potential slant for the delivery of therapeutics, especially in diseased skin via the openings of hair follicles. Recent origination might be achieved in the field of dermatological treatment with upgrading in the dermal localization of bio-actives into the precious skin region. This report looks at what has been done in the exploration of nanogels as drug carriers for topical therapy

Keywords: Nanogels, topical therapy, skin, hydrogels, polymers.