Abstract

ASSESSMENT OF PAIN RELIEVING ACTION (ANALGESIC) OF FLUID CONCENTRATE OF AESCHYNOMENE ASPERA LEAVES IN MALE WISTER ALBINO MICE

Assc. Prof. Uravakili Veeresh Kanna*, B. Mohammad Noor, Farash Naheed Hussain, Kanugala Swapna, Devareddy Aravind Kumar

ABSTRACT

Introduction: The medicinal properties of the Aschynomene aspera plant, which is frequently found in the southern part of India, have long been appreciated. Previous research has shown that it has anti-inflammatory properties, which could be useful for future research. However, there is no clear evidence that it has analgesic properties. With the utilization of tail flick technique, Tail immersion method, Acetic acid induced writhing test technique this review tries to evaluate the pain relieving viability of Aschynomene aspera plant remove in Wister Albino mice. Methods: Tail flick technique, Tail immersion method, Acetic acid induced writhing test strategy were utilized to decide the pain relieving viability of the plant extricate after it was incorporated utilizing Decoction technique. To survey the pain relieving influence, Wister pale skinned person mice were parted into four gatherings and Pain relieving boundaries were evaluated. Results: When compared to the lower dose of 200mg/kg, the plant extract Aschynomene aspera significantly reduced pain in Wister albino mice in all tests, including the Tail flick method, the Tail immersion method, and the Acetic acid induced writhing test Method. Conclusion: We concluded from the preceding tests that the aqueous decoction of Aschynomene aspera has an effective analgesic effect. Anyway further examinations ought to be finished for additional investigations.

Keywords: Tail flick, Tail immersion, Acetic acid, Decoction.