Abstract

REVIEW ON INTRA UTERINE DRUG DELIVERY SYSTEM

*Thiruvalluru Lavanya and P. Venkata Anuddep

ABSTRACT

An Intra uterine Device (IUD) is a small piece of plastic that is inserted by a clinician into the uterus to prevent pregnancy. IT is approximately half inches (3cm) in length. There are several different types of IUDs. The most common IUD id T-shaped and coated with copper. This can be left in the uterus for 2-5 years. Another type of IUD contains a hormone but it needs to be replaced once a year. Attached to the IUD are two plastic threads or strings that hang down through the cervix into the vagina. The cervix is the opening to the uterus. The IUD can also be used as an emergency method of birth control. An IUD is a good option for women who want a highly effective, long-term, easily reversible method of contraception. The human vagina represents a potential, accessible space that offers a valuable route for both local and systemic applications. Intra vaginal drug delivery is particularly appropriate for drugs associated with women’s health issues but may also have applications in general drug delivery within the female population. A range of drug delivery platforms suitable for intra vaginal administration are hydro-gels. Vaginal tablets, pessaries/suppositories, particulate systems, and intra- vaginal rings.

Keywords: Vagina, First pass Metabolism. Intra Vaginal Drug Delivery, Pessaries.