Abstract

A REVIEW OF THE IMPORTANCE OF HYDROGELS IN THE CONTROLLED DRUG DELIVERY SYSTEM

Shubham Sangle*, Sana Shaikh, Ketan Bhujbal and Apurva Dhainje

ABSTRACT

A particular kind of macromolecular network called a hydrogel is capable of holding a lot of aqueous solvents, which makes it perfect for biomedical uses including controlled drug delivery systems. To achieve the appropriate therapeutic result, the active pharmaceutical component can be delivered using the Control drug delivery system. The medication must also be given at the appropriate location and at a precisely regulated pace to ensure maximum efficacy and safety. They are employed in pharmaceutical production and medical practice since they were developed to duplicate biological tissues. The fundamentals, most current advancements, and techniques for bioactive chemical release from hydrogel-based drug delivery systems (DDS) are covered in this article. Due to their biocompatibility and likeness to natural tissue, hydrogels are employed in cell treatments, wound healing, cartilage/bone regeneration, prolonged release of medications, and wound healing. The paper also discusses the design and guiding principles for controlled drug distribution, including injectable hydrogels, cancer treatment dosages, distribution plans, concepts for stimuli-responsive hydrogels, and recent work on intelligent hydrogels. Additionally, the study emphasizes the characteristics of hydrogels, such mathematical modeling and drug release kinetics.

Keywords: Hydrogel, Controlled drug delivery system, Biocompatibility, Injectable Hydrogels, Intelligent Hydrogels.