Abstract

MALARIA IT CAUSES DRUG ADVANCEMENT AND RESISTANCE

Kripa Haldar*, Aaliya Naaz, Dr. Vijay Singh

ABSTRACT

Malaria is a serious worldwide health issue that results in a considerable amount of morbidity and mortality each year. A significant barrier to controlling malaria is the scarcity of treatment choices and the enormous challenge posed by the evolution of resistant parasite strains. Novel antimalarial medicines with single-dose cures, broad therapeutic potential, and unique mechanisms of action are desperately needed to avert a potential public health calamity. Antimalarial medication resistance has frequently jeopardized efforts to eradicate malaria and has historically resulted in a brief return of malaria cases and fatalities. Given the present focus on eradicating malaria, it is imperative to monitor drug resistance in clinical settings through the use of in vitro drug susceptibility assays and resistance marker studies. This will help ensure that a successful antimalarial medication policy is implemented. The emergence of resistance strains to widely used medications like chloroquine, the cost of treating malaria, and the absence of new, reasonably priced drugs are the issues that are restricting efforts to combat malaria. These characteristics highlight the ongoing need for research into novel antimalarial drug classes and a reevaluation of current antimalarial medications that may still be useful against resistant strains. 

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