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UV SPECTROPHOTOMETRIC ESTIMATION OF DILTIAZEM HYDROCHLORIDE IN BULK AND TABLET DOSAGE FORM
Rohan D. Kuntawar*, Sugandha V. Mulgund
ABSTRACT A simple, precise, accurate and economical spectrophotometric method has been developed for estimation of Diltiazem hydrochloride. The standard and sample solutions were prepared by using distilled water as a solvent. Quantitative determination of the drug was performed at 236 nm. The linearity was established over the concentration range of 6-16 μg/ml for Diltiazem hydrochloride with correlation coefficient value of 0.999. Precision studies showed that % relative standard deviation (%RSD) was within range of acceptable limits ( Keywords: Diltiazem hydrochloride, UV spectrophotometry, Validation [Download Article] [Download Certifiate] |
