Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

SYNTHESIS, SPECTROSCOPIC AND ANTIMICROBIAL STUDIES OF BINUCLEAR SCHIFF BASE COMPLEXES WITH N2O2 DONOR GROUPS

S.Vedanayaki*, P. Jayaseelan

ABSTRACT

A binuclear Schiff base, H2L, ligand synthesized by the reaction of 5-bromo-3-fluorosalicylaldehyde with 4, 4'– diaminodiphenylmethane in the molar ratio 2:1 forms complexes with transition metal ions such as Cu(II), Ni(II), V(IV) and Co(II). The elemental analysis, conductivity, IR, electronic, 1H NMR, LC-MS and magnetic susceptibility measurements were used to characterize the isolated ligand and its metal complexes. The ligand acts as dibasic with N2O2 tetradentate sites and two ligands coordinate with two metal ions to form binuclear complexes. The 1H - NMR data reveal that the Schiff base exists in enol – iminic form. The binding sites are the nitrogen atoms of azomethine groups and oxygen atoms of the phenolic groups. Substitution in phenyl ring of the complexes produces shift in the azomethine υ(C=N) stretching vibrational frequency. The non-electrolytic behavior of complexes indicates the absence of counter ions. EPR spectra provided further information to confirm the binuclear structure. On the basis of electronic spectral data and magnetic susceptibility measurements, suitable geometry has been proposed for each complex. The Schiff base ligand and its metal complexes were tested against four pathogenic bacteria (S. aureus and B. subtilis) as Gram – positive bacteria (E. coli and K. pneumoniae) as Gram – negative bacteria and one pathogenic fungi (A. fumigatus) to assess their antimicrobial properties.

Keywords: Schiff base, binuclear, anti-microbial activity.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More