Abstract

SYNTHESIS AND ACTIVITY OF COMPOUNDS AND DERIVATIVES FOR THEIR ANTI-PROLIFERATIVE ACTION

Pratiksha K.*, Sarthak J., Anushka B., Shubham B., Rohan B. and Shivaji G.

ABSTRACT

Anti-proliferative study focuses on the synthesis and evaluation of novel compounds and derivatives for their potential anti-proliferative activity. Through systematic design and analysis, the research aims to identify novel agents with enhanced anti-proliferative actions, providing valuable insights for potential therapeutic applications in combating normal cell growth. A diverse set of compounds are synthesized using various chemical methodologies and their structures are evaluated and characterized using spectroscopic techniques. These compounds are screened for their ability to inhibit cell proliferation using in vitro assays. Several compounds and derivatives are found to have significant anti-proliferative effect, suggesting their potential as therapeutic agents in the treatment of proliferative diseases including
cancer. By summarizing current research findings, the review offers a critical analysis of the strategies employed in designing these molecules and their efficacy in inhibiting cell proliferation. The synthesis methodologies, structure activity relationships and their potential mechanisms of action are discussed thereby providing a valuable resource for researchers and clinicians interested in advancing anti-proliferative therapeutics. This research of novel compounds for their anti-proliferative effects contributes to the development of new compounds with anti-proliferative properties and underscores the importance of chemical synthesis in drug discovery and development.

Keywords: Anti-proliferative action, in vitro assay, novel compounds, synthesis, cancer.