Abstract

NIOSOMES: A COMPREHENSIVE REVIEW OF STRUCTURE, PREPARATION AND APPLICATION

Drashti Dave* and Taufik Mulla

ABSTRACT

Niosomes are a novel drug delivery system that are finding application in drug targeting antineoplastic treatment, leishmaniasis treatment, delivery of peptide drugs, transdermal drug delivery systems, cosmetics, immunological application of peptide drugs, carriers for haemoglobin, sustained release etc. A niosome is a non-ionic surfactant based liposomes. It is formed by cholesterol with the use of other excipients. The various methods used in the formation of niosomes such as ether injection method, sonication, microfluidization, hand shaking method for the different types of niosomes. The goal of this article focuses on the recent advances in niosomal drug delivery, potential advantages over other delivery systems, formulation methods, methods of characterization, limitation of niosomes, comparision of niosomes v/s liposomes, application of niosomes, marketed products of niosomes and the current research in the field of niosomes.

Keywords: Niosome, Novel Drug Delivery, Method.