Abstract

PHYTOCHEMICAL ANALYSIS AND ACUTE TOXICITY STUDY OF MICHELIA CHAMPACA LEAVES

J. Priyananga*

ABSTRACT

Champaca Michelia Linn. Known as Champaca, it is a member of the Magnoliaceae family. It is a sizable medicinal plant that has been used for many years to treat many illnesses. Utilizing a 70% ethanol solvent, the powdered leaves of Michelia champaca were extracted. Up until the extract lost all of its color, the extraction procedure was continued. To extract the solvent, the extract was distilled under low pressure. Next, the extract was dried in a rotary evaporator set at 40˚C. Until further testing, the resultant dry extract, or EEMC, was kept in desiccators. The EEMC was found to include carbohydrates, flavonoids, saponins, fixed oils, steroids, alkaloids, and glycosides, according to preliminary phytochemical analyses. In mice evaluated for LD50 investigations at the maximum dose level of 2000 mg/kg, there was no observed mortality or aberrant behavior.

Keywords: Champaca Michelia Linn, Phytochemical screening, Acute toxicity study.