Photo Gallery

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from  7.454 to 7.632  due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • WJPPS: SEPTEMBER ISSUE PUBLISHED
  • SEPTEMBER 2021 Issue has been successfully launched on 1 September 2021.

Abstract

ANTI-INFLAMMATORY PROPERTIES OF THE METHANOL AND N- HEXANE EXTRACTS OF SANSEVIERA LIBERICA GÉRÔME AND LABROY IN RATS

*Awemu G.A., Agbai E.O, Anowi F. and Ramos G.F.

ABSTRACT

The methanol and n-hexane extracts of Sanseviera liberica were evaluated orally at the doses of 50, 100 and 200 mg/kg against carrageenan induced inflammation in rats. The methanol extract produced a dose dependent inhibition of inflammation with the highest percentage inhibition (55.2 %) occuring at the dose of 200 mg/kg after 4 hours while the 50 mg/kg group produced the least percentage inhibition of inflammation of 10.0 % after 2 hours. The n-hexane extract did not produce any significant inhibition of inflammation at the doses evaluated. Phytochemical screening of the extracts revealed the presence of carbohydrates, flavonoids, saponins, glycosides, alkaloids, steroids and terpenoids in the methanol extract while tannins, steroids and terpenoids were present in the n-hexane extract. Acute toxicity studies gave an LD50 value of 1350 mgkg-1. Results of this investigation vindicate the use of the polar extract by traditional medicine practitioners in the treatment of inflammation.

Keywords: Inflammation, extracts, rats, inhibition.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More