Abstract

A MINI REVIEW ON THE UTILIZATION OF FOSFOMYCIN IN RESPIRATORY INFECTIONS

Querequincia Joseph Mari B.*, Salvilla Remi Charlene M. and Dean Maria Donabelle U.

ABSTRACT

The main objective of this mini review article is to deliver ample data and information on the several studies demonstrating the utilization of Fosfomycin for respiratory related infections. Fosfomycin has long been used to treat bladder infections and given a single dose of 3 g in an oral preparation. There is also an intravenous preparation utilized for multidrug resistant bacterial infections. As an antibacterial agent it targets the cell wall of the microbe thereby having its broad spectrum of activity. This drug has a low incidence of very harmful adverse effects. Several studies showed that intravenous preparations of Fosfomycin showed satisfactory clinical response to patients. Other studies showed that it is clinically useful in treating infections due to various multidrug resistant bacteria such as penicillin-resistant pneumococci, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. Thus, Fosfomycin is a potential antibiotic agent that can be utilized to treat numerous diseases caused by bacterial species including respiratory related infections.

Keywords: Fosfomycin, Antibacterial, Respiratory infections, Intravenous.