Abstract

A SYSTEMIC REVIEW ON THE MECHANISM OF RESVERATROL AGAINST ANTIOXIDATIVE STRESS

Sun Chao, *Sreemoy Kanti Das and Wang Xiaoli

ABSTRACT

Resveratrol (RSV) is a poly-phenolic phytoalexin belonging to the stilbene family. It is a natural dietary plant compound that occurs mainly in grape skin and seeds but is also found in wines and various other types of plant foods, especially peanuts, berries, and tea. RSV has shown many bioactivities, such as antioxidant, anti-inflammatory, immunomodulatory, hypotensive, and hypolipidemic actions, as well as efficacies in the prevention and management of cancer, cardiovascular diseases, neurodegenerative diseases, and obesity. RSV is known for its anti-oxidative properties as a scavenger of reactive oxygen species (ROS) such as hydroxyl-, superoxide-, and metal-induced radicals. Here, we review the antioxidant properties, antioxidant stress effects and signaling pathways of RSV.

Keywords: immunomodulatory, hypotensive, and hypolipidemic.