Abstract

FORMULATION AND EVALUATION OF MOSQUITO REPELLANT SPRAY

Mallika Adhatrao, Azim Attar, Anjali Achaler and *Harshada Salunke (M. Pharm)

ABSTRACT

Mosquitoes are the blood sucking insects afflicting human beings and several mosquito species belonging to genera Anopheles, Culex and Aedes are responsible for mosquito-borne diseases. Therefore, the control of mosquitoes is an important public health concern around the world. As most of the synthetic mosquito repellent products and devices available in the market are reported to have harmful effects on human beings, the objective of the present study is to formulate effective plant-based mosquito repellent products with potent mosquito repellent activity with less side effects. The herbal mosquito repellant spray containing citronella as main mosquito repellant agent with tulsi essential oil and solvent ethanol and distilled water, emulsified with aid of Tween-80 is a formulation which spare its role in protecting the subjects from varieties of mosquitoes by providing the repellency layer over the skin of application with no skin irritancy were as bio-efficacy was tested by rubbing volunteer’s forearm with 1 ml test solution was exposed to open space of environment and to the areas between the lakes, where blood-seeking mosquitoes are found and the number of mosquitoes that aligned on the lower leg was recorded in each 10minutes of interval for 1 hour. Analysis was carried out as control group treated with ethanol, standard group treated with marketed odomos cream and test group treated with formulated herbal mosquito repellent spray and mosquito repellent activities of test group were found to be effective as similar as of marketed formulation of odomos, as per the determined percentage protection (%P).

Keywords: Mosquito repellant, Citronella, Spray, Emulsion, Essential Oil, %Protection.